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1. (WO2018136752) METHODS AND APPARATUS FOR PERFUSION AND ENVIRONMENT CONTROL OF MICROPLATE LABWARE

Pub. No.:    WO/2018/136752    International Application No.:    PCT/US2018/014447
Publication Date: Fri Jul 27 01:59:59 CEST 2018 International Filing Date: Sat Jan 20 00:59:59 CET 2018
IPC: C12M 1/32
C12M 3/06
C12M 1/00
C12M 1/12
C12M 1/34
C12M 3/00
Applicants: ESSEN INSTRUMENTS, INC. D.B.A. ESSEN BIOSCIENCE, INC.
Inventors: SCHROEDER, Kirk, S.
NEAGLE, Bradley, D.
ENDSLEY, Eric
APPLEDORN, Daniel
Title: METHODS AND APPARATUS FOR PERFUSION AND ENVIRONMENT CONTROL OF MICROPLATE LABWARE
Abstract:
Systems, methods, and apparatuses of controlling fluid flow are disclosed. An apparatus includes a first microplate having a first open portion and defining one or more first wells therein, a second microplate having a second open portion and defining one or more second wells therein, and a pneumatic lid constructed of styrene ethylene butylene styrene (SEBS). The pneumatic lid extends over the first open portion and the second open portion and includes one or more microfluidic channels that fluidly couple the one or more first wells to the one or more second wells. The pneumatic lid provides an airtight seal over the first microplate and the second microplate.