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1. (WO2018136559) METHODS FOR TREATING FLAVIVIRUSES AND ZIKA INFECTIONS

Pub. No.:    WO/2018/136559    International Application No.:    PCT/US2018/014108
Publication Date: Fri Jul 27 01:59:59 CEST 2018 International Filing Date: Thu Jan 18 00:59:59 CET 2018
IPC: A61K 31/70
A61K 31/47
A61K 38/00
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors: RANA, Tariq, M.
Title: METHODS FOR TREATING FLAVIVIRUSES AND ZIKA INFECTIONS
Abstract:
Provided are methods of treatment of Zika virus infection. Specifically, the disclosure provides methods of treating a Zika viral infection in a subject in need thereof, said methods comprising administering to said subject an effective amount of a therapeutic composition including an NS5 (non-structural (NS) protein 5) polymerase inhibitor. Further disclosed are NS5 inhibitors that can be used for the methods.