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1. (WO2018136425) PROTEINIC BIOMASS PREPARATION COMPRISING A NON-NATIVE ORGANISM OF THE CLOSTRIDIA CLASS
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Pub. No.: WO/2018/136425 International Application No.: PCT/US2018/013887
Publication Date: 26.07.2018 International Filing Date: 16.01.2018
IPC:
A23K 10/16 (2016.01) ,A23K 20/142 (2016.01) ,C12N 15/52 (2006.01)
[IPC code unknown for A23K 10/16][IPC code unknown for A23K 20/142]
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
52
Genes encoding for enzymes or proenzymes
Applicants:
WHITE DOG LABS, INC. [US/US]; 239 Lisa Drive New Castle, Delaware 19720, US
Inventors:
TRACY, Bryan P.; US
JONES, Shawn William; US
EYAL, Aharon M.; IL
Agent:
MUELLER, Robert W.; US
TURK, Arnold; US
GWINNELL, Harry J.; US
BERNSTEIN, Bruce H.; US
BOSHNICK, Bill; US
GREENBLUM, Neil; US
Priority Data:
62/447,17817.01.2017US
Title (EN) PROTEINIC BIOMASS PREPARATION COMPRISING A NON-NATIVE ORGANISM OF THE CLOSTRIDIA CLASS
(FR) PRÉPARATION DE BIOMASSE PROTÉIQUE COMPRENANT UN ORGANISME NON NATIF DE LA CLASSE CLOSTRIDIA
Abstract:
(EN) A proteinic biomass preparation comprising a non-native organism of the Clostridia class, which organism expresses (i) a modified aspartate kinase; (ii) a modified homoserine dehydrogenase; (iii) a modified homoserine kinase; (iv) a modified anthranilate synthase; (v) a functional lycopene pathway and the genes crtY, crtW, and crtZ; and/or (vi) a functional oleic acid pathway and the four gene operon (pfaABCD). Methods of producing proteinic biomass preparations are also described.
(FR) L'invention concerne une préparation de biomasse protéique comprenant un organisme non natif de la classe Clostridia, ledit organisme exprimant (i) une aspartate kinase modifiée ; (ii) une homosérine déshydrogénase modifiée ; (iii) une homosérine kinase modifiée ; (iv) une anthranilate synthase modifiée ; (v) une voie de lycopène fonctionnelle et les gènes crtY, crtW, et crtZ ; et/ou (vi) une voie d'acide oléique fonctionnelle et l'opéron à quatre gènes (pfaABCD). L'invention concerne également des procédés de production de préparations de biomasse protéique.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)