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1. (WO2018134584) POLIOVACCINE
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Pub. No.: WO/2018/134584 International Application No.: PCT/GB2018/050129
Publication Date: 26.07.2018 International Filing Date: 17.01.2018
A61K 39/13 (2006.01) ,A61P 31/14 (2006.01) ,A61K 39/12 (2006.01) ,C12N 7/04 (2006.01)
Applicants: THE SECRETARY OF STATE FOR HEALTH[GB/GB]; Richmond House 79 Whitehall London SW1A 2NS, GB
Inventors: MACADAM, Andrew; GB
Agent: GREGSON, Anna; GB
Priority Data:
Abstract: front page image
(EN) The invention provides poliovirus like particles,which comprise stabilised empty poliovirus capsids that retain their native antigenic properties. The invention also provides methods of identifying mutations useful in the production of such poliovirus like particles, methods of producing such poliovirus like particles and the use of such poliovirus like particles in methods of vaccinating against poliovirus.
(FR) L'invention concerne des particules de type poliovirus comprenant des capsides de poliovirus vides stabilisées qui conservent leurs propriétés antigéniques natives. L'invention concerne également des méthodes d'identification de mutations utiles dans la production de ces particules de type poliovirus, des procédés de production desdites particules, ainsi que l'utilisation de ces particules de type poliovirus dans des méthodes de vaccination contre le poliovirus.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)