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1. (WO2018132725) OPIOID AGONIST / ANTAGONIST COMBINATION DOSAGE FORMS
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Pub. No.: WO/2018/132725 International Application No.: PCT/US2018/013601
Publication Date: 19.07.2018 International Filing Date: 12.01.2018
IPC:
A61K 9/00 (2006.01) ,A61K 9/50 (2006.01) ,A61K 31/485 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
50
Microcapsules
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
47
Quinolines; Isoquinolines
485
Morphinan derivatives, e.g. morphine, codeine
Applicants:
KASHIV PHARMA LLC [US/US]; 995 US 202/206 Bridgewater, NJ 08807, US
Inventors:
SHAH, Navnit, H.; US
PHUAPRADIT, Wantanee; US
DESAI, Dipen; US
SANDHU, Harpreet, Kaur; US
VAKA, Siva Ram, Kiran; US
PATEL, Chanchal; US
TIWARI, Roshan, V.; US
THONGSUKMAK, Atsawin; US
Agent:
LEE, Sandra, S.; US
Priority Data:
62/446,24013.01.2017US
62/509,68322.05.2017US
Title (EN) OPIOID AGONIST / ANTAGONIST COMBINATION DOSAGE FORMS
(FR) FORMES POSOLOGIQUES À COMBINAISON AGONISTE/ANTAGONISTE OPIOÏDE
Abstract:
(EN) The presently disclosed subject matter provides a solid, immediate release, pharmaceutical multi-particulate dosage form containing at least one population of Opioid Particulates comprising one or more opioids; at least one population of Naloxone Particulates; and a population of Triggering Particulates. Each population of particulates is designed for a specific function to accomplish the desired combination of abuse deterrence and overdose protection.
(FR) La présente invention concerne une forme posologique pharmaceutique solide à libération immédiate, multiparticulaire contenant au moins une population de particules d'opioïde comprenant un ou plusieurs opioïdes; au moins une population de particules de Naloxone; et une population de particules de déclenchement. Chaque population de particules est conçue pour une fonction spécifique en vue de produire la combinaison souhaitée de dissuasion contre les abus et de protection contre les surdoses.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)