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1. (WO2018131593) METHOD FOR PRODUCING NUCLEIC ACID ARRAY, AND DEVICE FOR PRODUCING NUCLEIC ACID ARRAY
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Pub. No.: WO/2018/131593 International Application No.: PCT/JP2018/000303
Publication Date: 19.07.2018 International Filing Date: 10.01.2018
IPC:
C12N 15/09 (2006.01) ,C12M 1/00 (2006.01) ,G01N 33/53 (2006.01) ,G01N 37/00 (2006.01) ,G03F 7/004 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
M
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1
Apparatus for enzymology or microbiology
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
37
Details not covered by any other group of this subclass
G PHYSICS
03
PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
F
PHOTOMECHANICAL PRODUCTION OF TEXTURED OR PATTERNED SURFACES, e.g. FOR PRINTING, FOR PROCESSING OF SEMICONDUCTOR DEVICES; MATERIALS THEREFOR; ORIGINALS THEREFOR; APPARATUS SPECIALLY ADAPTED THEREFOR
7
Photomechanical, e.g. photolithographic, production of textured or patterned surfaces, e.g. printed surfaces; Materials therefor, e.g. comprising photoresists; Apparatus specially adapted therefor
004
Photosensitive materials
04
Chromates
Applicants:
株式会社ニコン NIKON CORPORATION [JP/JP]; 東京都港区港南二丁目15番3号 15-3, Konan 2-chome, Minato-ku, Tokyo 1086290, JP
Inventors:
川上 雄介 KAWAKAMI Yusuke; JP
Agent:
西澤 和純 NISHIZAWA Kazuyoshi; JP
大浪 一徳 ONAMI Kazunori; JP
小林 淳一 KOBAYASHI Junichi; JP
Priority Data:
2017-00331012.01.2017JP
Title (EN) METHOD FOR PRODUCING NUCLEIC ACID ARRAY, AND DEVICE FOR PRODUCING NUCLEIC ACID ARRAY
(FR) PROCÉDÉ DE PRODUCTION D'UN RÉSEAU D'ACIDES NUCLÉIQUES ET DISPOSITIF DE PRODUCTION D'UN RÉSEAU D'ACIDES NUCLÉIQUES
(JA) 核酸アレイの製造方法、及び核酸アレイ製造装置
Abstract:
(EN) This method for producing a nucleic acid array includes: a step (a) in which a layer (a PAG layer) of a resin composition including a photoacid generator (PAG) for generating an acid as a result of being exposed to light is formed on a solid phase having, immobilized therein, molecules having functional groups protected by acid-decomposable protective groups; a step (b) in which a desired position of the PAG layer is exposed to light; a step (c) in which the PAG layer which has been exposed to light is removed; and a step (d) in which the solid phase from which the PAG layer has been removed is brought into contact with a nucleotide derivative having acid-decomposable protective groups.
(FR) L'invention concerne un procédé de production d'un réseau d'acides nucléiques qui comprend : une étape (a) au cours de laquelle une couche (couche PAG) d'une composition de résine comprenant un générateur de photoacide (PAG) pour générer un acide après une exposition à la lumière est formée sur une phase solide ayant, immobilisées dans celle-ci, des molécules ayant des groupes fonctionnels protégés par des groupes protecteurs décomposables à l'acide ; une étape (b) au cours de laquelle une position souhaitée de la couche PAG est exposée à la lumière ; une étape (c) au cours de laquelle la couche PAG qui a été exposée à la lumière est retirée ; et une étape (d) au cours de laquelle la phase solide à partir de laquelle a été retirée la couche PAG est mise en contact avec un dérivé nucléotidique ayant des groupes protecteurs décomposables à l'acide.
(JA) (a)酸分解性保護基で保護された官能基を有する分子が固定化された固相上に、露光により酸を発生する光酸発生剤(PAG)を含有する樹脂組成物の層(PAG層)を形成する工程と、(b)前記PAG層の所望の位置を露光する工程と、(c)前記の露光後のPAG層を除去する工程と、(d)前記のPAG層を除去した固相を、酸分解性保護基を有するヌクレオチド誘導体と接触させる工程と、を含む核酸アレイの製造方法。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)