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1. (WO2018129207) METHODS FOR ASSEMBLING SCAVENGING PARTICLES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/129207 International Application No.: PCT/US2018/012414
Publication Date: 12.07.2018 International Filing Date: 04.01.2018
IPC:
A61K 47/68 (2017.01) ,A61K 47/69 (2017.01) ,A61P 35/00 (2006.01) ,B82Y 5/00 (2011.01) ,B82Y 30/00 (2011.01) ,A61K 9/51 (2006.01) ,A61K 9/14 (2006.01)
Applicants: NANOTICS, LLC[US/US]; 100 Shoreline Hwy, # 100B Mill Valley, CA 94941, US
Inventors: HAWTHORNE, Louis; US
DODGSON, John; GB
Agent: HALSTEAD, David, P.; US
ABELLEIRA, Susan, M.; US
BEOW, William, E.; US
AKHIEZER, Alexander; US
BLOUNT, Jennifer, V.; US
Priority Data:
62/442,32704.01.2017US
62/442,37604.01.2017US
Title (EN) METHODS FOR ASSEMBLING SCAVENGING PARTICLES
(FR) PROCÉDÉS D'ASSEMBLAGE DE PARTICULES ÉLIMINATRICES
Abstract:
(EN) The disclosure provides, methods for preparing scavenging particles, as well as methods for attaching capture agents to the particles. The disclosure further provides compositions that bind to and inhibit the biological activity of soluble biomolecules, as well as pharmaceutical compositions thereof. The compositions may comprise a plurality of particles that specifically bind a target, such as a soluble biomolecule or a biomolecule on the surface of a pathogen, to inhibit the target (or pathogen) from interacting with other molecules or cells. Also provided herein are a number of applications (e.g., therapeutic applications) in which the compositions are useful.
(FR) L'invention concerne des procédés de préparation de particules éliminatrices, ainsi que des procédés de fixation d'agents de capture aux particules. La présente invention concerne en outre des compositions qui se lient à des biomolécules solubles et inhibent leur activité biologique, ainsi que des compositions pharmaceutiques correspondantes. Les compositions peuvent comprendre une pluralité de particules qui se lient spécifiquement à une cible, par exemple une biomolécule soluble ou une biomolécule sur la surface d'un pathogène, afin d'empêcher la cible (ou le pathogène) d'entrer en interaction avec d'autres molécules ou cellules. L'invention concerne également plusieurs applications (par exemple, des applications thérapeutiques) dans lesquelles les compositions sont utiles.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)