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1. (WO2018128999) METHOD OF ADMINISTERING NITROXYL DONATING COMPOUNDS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/128999 International Application No.: PCT/US2018/012114
Publication Date: 12.07.2018 International Filing Date: 02.01.2018
IPC:
A61K 31/18 (2006.01) ,A61P 9/04 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
16
Amides, e.g. hydroxamic acids
18
Sulfonamides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9
Drugs for disorders of the cardiovascular system
04
Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Applicants: CARDIOXYL PHARMACEUTICALS, INC.[US/US]; 1450 Raleigh Road Exchange East, Suite 212 Chapel Hill, NC 27517, US
Inventors: KESSLER, Paul, D.; US
EWING, William, R.; US
BORENTAIN, Maria; FR
GARIMELLA, Tushar; US
STOCK, Elyse, G.; US
Agent: HORAN, Nina, R.; US
SRINIVASAN, Arthi, G.; US
POH, Phil, R.; US
BYRNE, Matthew, T.; US
Priority Data:
62/441,80303.01.2017US
62/549,93224.08.2017US
Title (EN) METHOD OF ADMINISTERING NITROXYL DONATING COMPOUNDS
(FR) PROCÉDÉ D'ADMINISTRATION DE COMPOSÉS DONNEURS DE NITROXYLE
Abstract:
(EN) The disclosed subject matter provides methods of using nitroxyl donating compounds and pharmaceutical compositions comprising such compounds in a dose escalation regimen.
(FR) La présente invention concerne des procédés d'utilisation de composés donneurs de nitroxyle et des compositions pharmaceutiques comprenant de tels composés dans un régime posologique croissant.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)