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1. (WO2018128826) COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS

Pub. No.:    WO/2018/128826    International Application No.:    PCT/US2017/067750
Publication Date: Fri Jul 13 01:59:59 CEST 2018 International Filing Date: Thu Dec 21 00:59:59 CET 2017
IPC: A61K 38/00
A61K 38/04
A61K 38/12
A61K 38/14
Applicants: CIDARA THERAPEUTICS, INC.
Inventors: AKERS-RODRIGUEZ, Suzanne
BALKOVEC, James, Michael
BENSEN, Daniel, C.
BLIZZARD, Timothy
BORCHARDT, Allen
BRADY, Thomas, Patrick
CHEN, Zhi-Yong
DO, Quyen-Quyen, Thuy
FORTIER, Joanne, M.
JIANG, Wanlong
LAM, Thanh
TARI, Leslie, W.
NONCOVICH, Alain
Title: COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS
Abstract:
Compositions and methods for the treatment of bacterial infections include conjugates containing an Fc domain covalently linked to one or more monomers of cyclic heptapeptides or one or more dimers of cyclic heptapeptides. In particular, conjugates can be used in the treatment of bacterial infections caused by Gram-negative bacteria.