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1. (WO2018128163) INTESTINAL MICROFLORA IMPROVING AGENT, AND USE THEREOF

Pub. No.:    WO/2018/128163    International Application No.:    PCT/JP2017/047236
Publication Date: Fri Jul 13 01:59:59 CEST 2018 International Filing Date: Fri Dec 29 00:59:59 CET 2017
IPC: A61K 31/7016
A23L 33/125
A61P 1/00
A61P 1/04
Applicants: NIIGATA UNIVERSITY
国立大学法人新潟大学
ISHIKAWA PREFECTURAL PUBLIC UNIVERSITY CORPORATION
石川県公立大学法人
Inventors: NAKAI Hiroyuki
中井 博之
KURIHARA Shin
栗原 新
KATAYAMA Takane
片山 高嶺
KITAOKA Motomitsu
北岡 本光
Title: INTESTINAL MICROFLORA IMPROVING AGENT, AND USE THEREOF
Abstract:
This intestinal microflora improving agent contains, as an active ingredient, galactosyl-β-1,4-rhamnose or an analog thereof, or pharmaceutically acceptable salts of these substances. A pharmaceutical composition for improving intestinal microflora contains the intestinal microflora improving agent and a pharmaceutically acceptable carrier and/or a diluent. A food/beverage includes the intestinal microflora improving agent. A method for promoting the proliferation of Bifidobacterium is a method for administering galactosyl β-1,4-rhamnose or an analog thereof, or pharmaceutically acceptable salts of these substances. A method for inhibiting the proliferation of Clostridium difficile is a method for administering galactosyl β-1,4-rhamnose or an analog thereof, or pharmaceutically acceptable salts of these substances, to a subject carrying Clostridium difficile.