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1. (WO2018127801) PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION

Pub. No.:    WO/2018/127801    International Application No.:    PCT/IB2018/050022
Publication Date: Fri Jul 13 01:59:59 CEST 2018 International Filing Date: Wed Jan 03 00:59:59 CET 2018
IPC: C07D 401/14
C07D 413/14
C07D 417/14
C07D 487/04
C07D 491/048
C07D 491/147
A61K 31/444
A61P 31/18
Applicants: VIIV HEALTHCARE UK (NO.5) LIMITED
Inventors: BOWSHER, Michael S.
DESKUS, Jeffrey
EASTMAN, Kyle J.
GILLIS, Eric P
FRENNESSON, David B
IWUAGWU, Christiana
NAIDU, B. Narasimhulu
PARCELLA, Kyle E.
PEESE, Kevin M
SAULNIER, Mark G
SIVAPRAKASAM, Prasanna
Title: PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
Abstract:
Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.