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1. (WO2018127666) MICROFLUIDIC SYSTEM FOR HANDLING BIOLOGICAL CELLS
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Pub. No.: WO/2018/127666 International Application No.: PCT/FR2018/050022
Publication Date: 12.07.2018 International Filing Date: 05.01.2018
IPC:
C12M 3/06 (2006.01) ,B01L 3/00 (2006.01) ,C12M 1/26 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
M
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3
Tissue, human, animal or plant cell, or virus culture apparatus
06
with filtration, ultrafiltration, inverse osmosis or dialysis means
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
L
CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3
Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
M
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1
Apparatus for enzymology or microbiology
26
Inoculator or sampler
Applicants:
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES [FR/FR]; Bat le Ponant 25 rue Leblanc 75015 Paris, FR
Inventors:
AGACHE, Vincent; FR
CASSET, Fabrice; FR
FANGET, Stéphane; FR
FOUILLET, Yves; FR
MILLET, Arnaud; FR
Agent:
GUERRE, Fabien; FR
Priority Data:
17 5013406.01.2017FR
Title (EN) MICROFLUIDIC SYSTEM FOR HANDLING BIOLOGICAL CELLS
(FR) SYSTEME MICROFLUIDIQUE DE MANIPULATION DE CELLULES BIOLOGIQUES
Abstract:
(EN) System for handling biological cells, comprising a main channel (6) comprising an inlet end (6.1) and an outlet end (6.2), and, at least over a first portion from the inlet end (6.1), comprising a cross section such that a cell (C) circulating in said portion undergoes mechanical stresses, first means for detecting (10) the presence of a cell at the inlet end of the main channel (6) and at least one access zone (8) opening into the main channel (6) between its inlet end (6.1) and its outlet end (6.2) in said first portion, in order to make it possible to exert an action on the cell (C), the system also comprising means for displacing (P) the cell in order to control the displacement of the cell between the inlet end (6.1) and the outlet end (6.2).
(FR) Système de manipulation de cellules biologiques comportant un canal principal (6) comportant une extrémité d'entrée (6.1) et une extrémité de sortie (6.2), au moins sur une première portion à partir de son entrée d'extrémité (6.1), une section transversale telle qu'une cellule (C) circulant dans ladite portion subit des contraintes mécaniques, des premiers moyens de détection (10) de la présence d'une cellule au niveau de l'extrémité d'entrée du canal principal (6) et au moins une zone d'accès (8) débouchant dans le canal principal (6) entre son extrémité d'entrée (6.1) et son extrémité de sortie (6.2) dans ladite première portion, afin de permettre d'exercer une action sur la cellule (C), le système comportant également des moyens de déplacement (P) de la cellule pour contrôler le déplacement la cellule entre l'extrémité d'entrée (6.1) et l'extrémité de sortie (6.2).
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: French (FR)
Filing Language: French (FR)