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1. (WO2018127016) LIGHT-RESPONSIVE LIPOSOME, PREPARATION METHOD AND APPLICATION THEREOF

Pub. No.:    WO/2018/127016    International Application No.:    PCT/CN2017/120158
Publication Date: Fri Jul 13 01:59:59 CEST 2018 International Filing Date: Sat Dec 30 00:59:59 CET 2017
IPC: C07C 245/08
A61K 9/127
A61K 31/704
A61K 47/28
A61K 47/24
A61K 47/18
Applicants: ANYCHECK INFORMATION TECHNOLOGIES CO., LTD.
深圳市前海安测信息技术有限公司
Inventors: ZHANG, Guanjing
张贯京
GE, Xinke
葛新科
GAO, Weiming
高伟明
Title: LIGHT-RESPONSIVE LIPOSOME, PREPARATION METHOD AND APPLICATION THEREOF
Abstract:
A light-responsive liposome, a preparation method and an application thereof. The light-responsive liposome comprises a phospholipid, cholesterol and an azobenzene derivative containing a quaternary ammonium salt group at a molar ratio of 1-2:1-2:1-2. The light-responsive liposome may respond to ultraviolet light, and may achieve controlled release of a drug in an inner portion of the liposome by means of ultraviolet light irradiation.