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1. (WO2018126180) METHODS FOR THE DETECTION OF TAU PROTEIN AGGREGATES

Pub. No.:    WO/2018/126180    International Application No.:    PCT/US2017/069024
Publication Date: Fri Jul 06 01:59:59 CEST 2018 International Filing Date: Sat Dec 30 00:59:59 CET 2017
IPC: G01N 33/68
Applicants: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
Inventors: CAUGHEY, Byron Winslow
SAIJO, Eri
KRAUS, Allison Lindsey
METRICK, II, Michael Anthony
Title: METHODS FOR THE DETECTION OF TAU PROTEIN AGGREGATES
Abstract:
Methods are disclosed herein for determining whether a subject has a Tauopathy, such as Pick disease, Alzheimer disease, progressive supranuclear palsy (PSP), corticobasal degeneration (CBD) or argyrophilic grain disease (AGD). These methods utilize an amyloid seeding assay.