Search International and National Patent Collections

1. (WO2018126143) ORGANIC COMPOUNDS

Pub. No.:    WO/2018/126143    International Application No.:    PCT/US2017/068968
Publication Date: Fri Jul 06 01:59:59 CEST 2018 International Filing Date: Sat Dec 30 00:59:59 CET 2017
IPC: A61K 31/395
A61K 31/495
A61K 31/4985
C07D 487/00
C07D 487/02
C07D 487/04
Applicants: INTRA-CELLULAR THERAPIES, INC.
Inventors: LI, Peng
DAVIS, Robert
Title: ORGANIC COMPOUNDS
Abstract:
The invention relates to particular substituted heterocycle fused gamma-carbolines, their prodrugs, in free, solid, pharmaceutically acceptable salt and/or substantially pure form as described herein, pharmaceutical compositions thereof, and methods of use in the treatment of diseases involving the 5-HT2A receptor, the serotonin transporter (SERT), pathways involving the dopamine D1 and D2 receptor signaling system, and/or the μ-opioid receptor.