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Pub. No.: WO/2018/126049 International Application No.: PCT/US2017/068777
Publication Date: 05.07.2018 International Filing Date: 28.12.2017
IPC:
A61K 47/10 (2017.01) ,A61K 47/14 (2017.01) ,A61K 47/26 (2006.01) ,C07C 31/08 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
08
containing oxygen
10
Alcohols; Phenols; Salts thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
08
containing oxygen
14
Esters of carboxylic acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
26
Carbohydrates
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
31
Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
02
Monohydroxylic acyclic alcohols
08
Ethanol
Applicants: DURECT CORPORATION[US/US]; 10260 Bubb Road Cupertino, California 95014-4166, US
SANTEN PHARMACEUTICAL CO., LTD.[JP/JP]; 9-19, Shimoshinjo 3-chome Higashiyodogawa-ku Osaka-shi, Osaka 533-8651, JP
Inventors: TAMRAZ, Wilma; US
SU, Huey-Ching Lin; US
LIN, WeiQi; US
YAMADA, Kazuhito; JP
MATSUMOTO, Naoki; JP
MUDUMBA, Sreenivasu; US
OKABE, Komei; JP
Agent: MUELLER, Robert W.; US
MYERS-PAYNE, Sean C.; US
BERNSTEIN, Bruce H.; US
GREENBLUM, Neil F.; US
Priority Data:
15/637,40129.06.2017US
2,972,29629.06.2017CA
62/440,65830.12.2016US
PCT/US2017/03996829.06.2017US
Title (EN) DEPOT FORMULATIONS
(FR) PRÉPARATIONS DÉPÔT
Abstract:
(EN) Pharmaceutical compositions comprising an active pharmaceutical ingredient, a high viscosity liquid carrier material, a hydrophobic solvent, and a hydrophilic solvent are disclosed. Also disclosed are methods of manufacturing and using the compositions. The compositions are suitable for use, e.g., as depot formulations.
(FR) L'invention concerne des compositions pharmaceutiques comprenant un ingrédient pharmaceutique actif, un véhicule liquide à viscosité élevée, un solvant hydrophobe et un solvant hydrophile. L'invention concerne également des procédés de production et d'utilisation desdites compositions. Ces compositions sont appropriées pour être utilisées, par exemple, comme préparations dépôt.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)