A system may include a power supply (100) configurable to generate any of a plurality of output voltages on a power supply output node. The system also may include a voltage auto-detection power distribution (PD) controller (120) coupled to the power supply (102). The voltage auto- detection PD controller (120) is configured to monitor an input signal for detection of presence of a device (80) coupled to the system via a cable (90) and assert combinations of a plurality of control signals. For each combination of control signals, the voltage auto-detection PD controller (120) measures a value of an output voltage from the power supply (102), stores the measured value, and generates a plurality of packets for transmission to the device (80). Each packet contains a parameter indicative of a measured output voltage.