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1. (WO2018125901) MODIFICATION OF SURFACE PROPERTIES OF MICROFLUIDIC DEVICES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/125901 International Application No.: PCT/US2017/068497
Publication Date: 05.07.2018 International Filing Date: 27.12.2017
IPC:
C09D 5/16 (2006.01) ,C09D 183/04 (2006.01)
C CHEMISTRY; METALLURGY
09
DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
D
COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
5
Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
16
Anti-fouling paints; Underwater paints
C CHEMISTRY; METALLURGY
09
DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
D
COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
183
Coating compositions based on macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon, with or without sulfur, nitrogen, oxygen, or carbon only; Coating compositions based on derivatives of such polymers
04
Polysiloxanes
Applicants: BIO-RAD LABORATORIES, INC.[US/US]; 1000 Alfred Nobel Drive Hercules, California 94547, US
Inventors: RITCHEY, Joshua; US
XUE, Yi; US
MELTZER, Robert; US
Agent: ROBERGE, Christopher; US
HINSCH, Matthew E.; US
RACZKOWSKI, David B.; US
FLANAGAN, Lisa Dornbach; US
DODDRIDGE, Zara A.; US
CHANG, James K.; US
SHURTZ, Kenneth; US
MAO, Yifan; US
Priority Data:
62/439,56228.12.2016US
Title (EN) MODIFICATION OF SURFACE PROPERTIES OF MICROFLUIDIC DEVICES
(FR) MODIFICATION DES PROPRIÉTÉS DE SURFACE DE DISPOSITIFS MICROFLUIDIQUES
Abstract:
(EN) Compositions, devices, and methods are disclosed for the modification of polymer surfaces with coatings having a dispersion of silicone polymer and hydrophobic silica. The surface coatings provide the polymer surface with high hydrophobicity, as well as increased resistance to biofouling with proteinaceous material. The polymer surfaces can be particularly useful in microfluidic devices and methods that involve the contacting of the covalently modified polymer surfaces with emulsions of aqueous droplets containing biological macromolecules within an oil carrier phase.
(FR) L'invention concerne des compositions, des dispositifs et des procédés pour la modification de surfaces polymères avec des revêtements comprenant une dispersion de polymère de silicone et de silice hydrophobe. Les revêtements de surface confèrent à la surface polymère une hydrophobicité élevée, ainsi qu'une résistance accrue à l'encrassement biologique par un matériau protéique. Les surfaces polymères peuvent être particulièrement utiles dans des dispositifs et des procédés microfluidiques qui impliquent la mise en contact des surfaces de polymère modifiées de manière covalente avec des émulsions de gouttelettes aqueuses contenant des macromolécules biologiques dans une phase de support huileuse.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)