Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2018124959) MICROPARTICLES FROM STREPTOCOCCUS PNEUMONIAE AS VACCINE ANTIGENS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/124959 International Application No.: PCT/SE2017/051323
Publication Date: 05.07.2018 International Filing Date: 21.12.2017
IPC:
C07K 14/315 (2006.01) ,A61K 39/02 (2006.01) ,A61K 39/00 (2006.01)
[IPC code unknown for C07K 14/315][IPC code unknown for A61K 39/02][IPC code unknown for A61K 39]
Applicants:
HENRIQUES NORMARK, Birgitta [SE/SE]; SE
Inventors:
HENRIQUES NORMARK, Birgitta; SE
CODEMO, Mario; SE
IOVINO, Federico; SE
MUSCHIOL, Sandra; SE
NORMARK, Staffan; SE
NYUNT, Sun; SE
Agent:
NOVITAS PATENT AB; P.O. Box 55557 10204 Stockholm, SE
Priority Data:
1651746-828.12.2016SE
Title (EN) MICROPARTICLES FROM STREPTOCOCCUS PNEUMONIAE AS VACCINE ANTIGENS
(FR) MICROPARTICULES DE STREPTOCOCCUS PNEUMONIAE EN TANT QU'ANTIGÈNES DE VACCIN
Abstract:
(EN) An isolated Streptococcus pneumoniae membrane vesicle microparticle (MP), wherein said MP comprises: the protein Ply at the level of ≥0.070 µg/µg total protein in the MP; and/or the protein LytA at the level of≥0.070 µg/µg total protein in the MP; and/or the protein PspC at the level of≥0.130 µg/µg total protein in the MP; and/or the protein RrgB at the level of≥0.020 µg/µg total protein in the MP. Compositions comprising such MPs. Uses thereof in particular in immunization, as well as methods of manufacture thereof.
(FR) L'invention concerne une microparticule (MP) de vésicule membranaires de Streptococcus pneumoniae isolée, ladite MP comprenant : la protéine Ply en quantité ≥ 0 070 µg/µg des protéines totales dans la MP; et/ou la protéine LytA en quantité ≥ 0 070 µg/µg de protéines totales dans la MP; et/ou la protéine PspC en quantité ≥ 0,130 µg/µg de protéines totales dans la MP; et/ou la protéine RrgB en quantité ≥ 0,020 µg/µg de protéines totales dans la MP. L'invention concerne également des compositions comprenant ces MP. L'invention concerne en outre des utilisations associées, en particulier dans l'immunisation, ainsi que des procédés de fabrication associés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)