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1. (WO2018124887) ELECTROSPUN MATRIX AND METHOD
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Pub. No.: WO/2018/124887 International Application No.: PCT/NZ2017/050177
Publication Date: 05.07.2018 International Filing Date: 28.12.2017
Chapter 2 Demand Filed: 26.10.2018
IPC:
A61L 27/60 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
50
Materials characterised by their function or physical properties
60
Materials for use in artificial skin
Applicants:
AUCKLAND UNISERVICES LTD [NZ/NZ]; Level 10, UniServices House 70 Symonds Street Auckland, 1010, NZ
Inventors:
DUNBAR, Peter Roderick; NZ
FEISST, Vaughan J.; NZ
KERR-PHILIPS, Thomas; NZ
LOCKE, Michelle Barbra; NZ
MALMSTROM-PENDRED, Jenny; NZ
TRAVAS-SEJDIC, Jadranka; NZ
WRIGHT, Bryon; NZ
Agent:
CATALYST INTELLECTUAL PROPERTY; Level 5, 45 Johnston Street Wellington, 6011, NZ
Priority Data:
1622340.628.12.2016GB
Title (EN) ELECTROSPUN MATRIX AND METHOD
(FR) MATRICE ÉLECTROFILÉE ET PROCÉDÉ
Abstract:
(EN) The present disclosure relates a biocompatible biodegradable polymer matrix which serves as a template for the growth of differentiated skin tissue comprising a dermis and an epidermis, the combination of the matrix and the differentiated skin, the method of preparing the same and the tissue obtainable from said method. The disclosure also extends to use of the differentiated skin in treatment. Thus, there is provided a matrix of electrospun fibres for growing differentiated skin tissue prepared by electrospinning solution of a biocompatible biodegradable polymer, wherein the electrospun fibres are about 0.3 µm to about 5 µm in diameter for example 1 to 5 µm, such as 1, 1.5, 2, 2.5, 3, 3.5, 4, or 4.5 µm
(FR) La présente invention concerne une matrice polymère biodégradable biocompatible qui sert de gabarit pour la croissance de tissu de peau différencié, comprenant un derme et un épiderme, la combinaison de la matrice et de la peau différenciée, son procédé de préparation et le tissu pouvant être obtenu à partir dudit procédé. L'invention concerne également l'utilisation de la peau différenciée dans le traitement. Ainsi, l'invention concerne une matrice de fibres électrofilées pour la croissance de tissu de peau différencié préparé par électrofilage d'une solution d'un polymère biodégradable biocompatible, les fibres électrofilées étant d'environ 0,3 µm à environ 5 µm de diamètre, par exemple de 1 à 5 µm, telles que 1 ; 1,5 ; 2 ; 2,5 ; 3 ; 3,5 ; 4 ou 4,5 µm.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)