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1. (WO2018124766) CHIMERIC ANTIGEN RECEPTOR AND NATURAL KILLER CELLS EXPRESSING SAME

Pub. No.:    WO/2018/124766    International Application No.:    PCT/KR2017/015635
Publication Date: Fri Jul 06 01:59:59 CEST 2018 International Filing Date: Fri Dec 29 00:59:59 CET 2017
IPC: C07K 14/725
C07K 14/705
C07K 14/735
C07K 16/00
C12N 5/0783
A61K 35/17
Applicants: GREEN GROSS LAB CELL CORPORATION
주식회사 녹십자랩셀
Inventors: HWANG, Yu Kyeong
황유경
CHO, Sung Yoo
조성유
WON, Sung Yong
원성용
LIM, Ho Yong
임호용
HER, Jung Hyun
허정현
JUNG, Mi Young
정미영
KIM, Hyun Ah
김현아
GWON, Su Hyun
권수현
LEE, Eun Sol
이은솔
KIM, Han Sol
김한솔
Title: CHIMERIC ANTIGEN RECEPTOR AND NATURAL KILLER CELLS EXPRESSING SAME
Abstract:
The present invention relates to a chimeric antigen receptor and natural killer cells expressing the same and, more particularly, to a chimeric antigen receptor (CAR) comprising an intracellular signaling domain including all or a part of an OX40 ligand (CD252), thereby having an excellent anticancer activity enhancing effect on immune cells, and immune cells expressing the same.