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|1. (WO2018124644) NOVEL METHOD FOR PREPARING THIENOPYRIMIDINE COMPOUND AND INTERMEDIATE|
|Applicants:||HANMI PHARM. CO., LTD.
|Inventors:||KIM, Hee Cheol
HA, Tae Hee
SUH, Kwee Hyun
|Title:||NOVEL METHOD FOR PREPARING THIENOPYRIMIDINE COMPOUND AND INTERMEDIATE|
The present invention relates to a novel method for preparing a thienopyrimidine compound having activities of selectively inhibiting tyrosine kinase, particularly mutant epidermal growth factor receptor tyrosine kinase, and a novel intermediate used therefor. The present invention can industrially mass-produce, more simply and efficiently than the prior art, a compound of formula (1), which is useful as a therapeutic agent for non-small cell lung cancer induced by mutant epidermal growth factor receptor tyrosine kinase.