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1. (WO2018124640) CANCER-TREATING PHARMACEUTICAL COMPOSITION INHIBITING EXPRESSION OF CCND3 OR PAK2 GENE
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Pub. No.: WO/2018/124640 International Application No.: PCT/KR2017/015260
Publication Date: 05.07.2018 International Filing Date: 21.12.2017
IPC:
A61K 48/00 (2006.01) ,C12Q 1/68 (2006.01) ,G01N 33/68 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
Applicants: KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES[KR/KR]; 75, Nowon-ro Nowon-gu, Seoul 01812, KR
Inventors: KOO, Kyung Hee; KR
KWON, Hee Chung; KR
SONG, Jie Young; KR
Agent: Y.P.LEE, MOCK & PARTNERS; 12F Daelim Acrotel, 13 Eonju-ro 30-gil Gangnam-gu, Seoul 06292, KR
Priority Data:
10-2016-017912726.12.2016KR
Title (EN) CANCER-TREATING PHARMACEUTICAL COMPOSITION INHIBITING EXPRESSION OF CCND3 OR PAK2 GENE
(FR) COMPOSITION PHARMACEUTIQUE DE TRAITEMENT DU CANCER INHIBITRICE DE L'EXPRESSION DU GÈNE CCND3 OU PAK2
(KO) CCND3 또는 PAK2 유전자의 발현을 저해하는 암을 치료하기 위한 약학적 조성물
Abstract:
(EN) A substance inhibiting the expression of the CCND3 or PAK2 gene, the substance containing a nucleotide such as miR-4779, may be efficiently used for preventing or treating cancer. In addition, the substance inhibiting the expression of the CCND3 or PAK2 gene may be screened so as to enable the selection of a candidate substance for preventing or treating cancer.
(FR) L'invention concerne une substance inhibitrice de l'expression du gène CCND3 ou PAK2, la substance contenant un nucléotide tel que miR-4779, qui peut être utilisée efficacement pour la prévention ou le traitement du cancer. En outre, la substance inhibitrice de l'expression du gène CCND3 ou PAK2 peut être criblée afin de permettre la sélection d'une substance candidate pour la prévention ou le traitement du cancer.
(KO) miR-4779 등의 뉴클레오티드를 포함하는, CCND3 또는 PAK2 유전자의 발현을 저해하는 물질은 암을 예방 또는 치료하기 위해 효율적으로 이용될 수 있다. 또한, CCND3 또는 PAK2 유전자의 발현을 저해하는 물질을 스크리닝하여 암을 예방 또는 치료하기 위한 후보 물질을 선별할 수 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)