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1. (WO2018124497) PHARMACEUTICAL COMPOSITE PREPARATION CONTAINING DAPAGLIFLOZIN L-PROLINE AND ANTIDIABETIC AGENT
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Pub. No.: WO/2018/124497 International Application No.: PCT/KR2017/013690
Publication Date: 05.07.2018 International Filing Date: 28.11.2017
IPC:
A61K 9/20 (2006.01) ,A61K 9/24 (2006.01) ,A61K 31/7034 (2006.01) ,A61K 31/155 (2006.01) ,A61K 45/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
22
Sustained or differential release type
24
Layered or laminated unitary dosage forms
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7028
Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
7034
attached to a carbocyclic compound, e.g. phloridzin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
13
Amines, e.g. amantadine
155
Amidines (), e.g. guanidine (H2N-C(NH)-NH2), isourea (HNC(OH)NH2), isothiourea (HNC(SH)-NH2)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Applicants:
한미약품 주식회사 HANMI PHARM. CO., LTD. [KR/KR]; 경기도 화성시 팔탄면 무하로 214 214, Muha-ro, Paltan-myeon, Hwaseong-si Gyeonggi-do 18536, KR
Inventors:
권세호 KWEON, Se Ho; KR
탁진욱 TAK, Jin Wook; KR
김진철 KIM, Jin Cheul; KR
김용일 KIM, Yong Il; KR
박재현 PARK, Jae Hyun; KR
우종수 WOO, Jong Soo; KR
Agent:
최은선 CHOI, Eun Sun; KR
Priority Data:
10-2016-018403630.12.2016KR
Title (EN) PHARMACEUTICAL COMPOSITE PREPARATION CONTAINING DAPAGLIFLOZIN L-PROLINE AND ANTIDIABETIC AGENT
(FR) PRÉPARATION COMPISITE PHARMACEUTIQUE CONTENANT DE LA DAPAGLIFLOZINE L-PROLINE ET UN AGENT ANTIDIABÉTIQUE
(KO) 다파글리플로진 L-프롤린과 항당뇨병제를 포함하는 약제학적 복합 제제
Abstract:
(EN) The present invention relates to a pharmaceutical composite preparation containing dapagliflozin L-proline and at least one antidiabetic agent. Specifically, the present invention provides a pharmaceutical composite preparation containing dapagliflozin L-proline and additionally, metformin and/or a DPP-IV inhibitor, and relates to a composite preparation having excellent content uniformity and elution properties and high bioavailability.
(FR) La présente invention concerne une préparation composite pharmaceutique contenant de la dapagliflozine L-proline et au moins un agent antidiabétique. De façon spécifique, la présente invention concerne une préparation composite pharmaceutique contenant de la dapagliflozine L-proline et, en plus, de la metformine et/ou un inhibiteur de DPP-IV, et concerne une préparation composite ayant d'excellentes propriétés d'uniformité de contenu et d'élution ainsi qu'une biodisponibilité élevée.
(KO) 본 발명은 다파글리플로진 L-프롤린과 하나 이상의 항당뇨병제를 포함하는 약제학적 복합 제제에 대한 것이다. 구체적으로, 다파글리플로진 L-프롤린에 메트포르민 및/또는 DPP-IV 억제제를 추가로 포함하는 약제학적 복합 제제를 제공하며, 우수한 함량균일성 및 용출특성을 가지며 생체이용율이 높은 복합 제제에 관한 것이다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)