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|1. (WO2018124282) PHARMACEUTICAL COMPOSITION AND METHOD FOR PRODUCING SAME|
|Applicants:||TOYAMA CHEMICAL CO., LTD.
|Title:||PHARMACEUTICAL COMPOSITION AND METHOD FOR PRODUCING SAME|
The present invention addresses the problem of providing a pharmaceutical composition that contains a high concentration of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof and masks the bitter taste thereof, and a method for producing the pharmaceutical composition. The present invention provides a pharmaceutical composition containing granules that have a core including 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof and a binder, and have a polymer layer coated on the surface of the core, the granules having a roundness of 0.8 or higher, and the amount of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salt thereof contained in the granules being 30-90% by mass.