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1. (WO2018124155) PRODUCTION METHOD FOR CONDITIONAL KNOCKOUT ANIMAL

Pub. No.:    WO/2018/124155    International Application No.:    PCT/JP2017/046837
Publication Date: Fri Jul 06 01:59:59 CEST 2018 International Filing Date: Thu Dec 28 00:59:59 CET 2017
IPC: C12N 15/09
A01K 67/027
Applicants: NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
国立大学法人群馬大学
Inventors: HATADA, Izuho
畑田 出穂
HORII, Takuro
堀居 拓郎
Title: PRODUCTION METHOD FOR CONDITIONAL KNOCKOUT ANIMAL
Abstract:
Provided are a production method for a conditional knockout animal and associated techniques (e.g. an effective production method for a floxed animal). An animal having a pair of recombinase recognition sequences on a chromosome, i.e. a floxed animal, is produced by introducing a recombinase recognition sequence such as loxP at each end of a target site on a chromosome at different times.