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|1. (WO2018124132) OIL-IN-WATER EMULSION PREPARATION CONTAINING BACTERIAL CELL WALL SKELETON COMPONENT|
|Applicants:||JAPAN BCG LABORATORY
|Title:||OIL-IN-WATER EMULSION PREPARATION CONTAINING BACTERIAL CELL WALL SKELETON COMPONENT|
Bacterial CWS having a mycolic acid moiety and some arabinogalactan exposed on the surface was prepared, whereby when the prepared bacterial CWS was used to prepare an oil-in-water emulsion, it was possible to prepare a novel oil-in-water emulsion having the arabinogalactan of the bacterial CWS protruding and exposed on the surface of oil particles and a lyophilized preparation of the oil-in-water emulsion. This emulsion preparation exhibits superior immunostimulatory activity together with exceptional stability. As a result, new immunotherapeutic agents for cancer could be prepared using this emulsion preparation.