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1. (WO2018124067) RADIATION DAMAGE PROTECTIVE AGENT
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Pub. No.: WO/2018/124067 International Application No.: PCT/JP2017/046633
Publication Date: 05.07.2018 International Filing Date: 26.12.2017
IPC:
A61K 33/00 (2006.01) ,A61G 10/02 (2006.01) ,A61H 33/14 (2006.01) ,A61P 7/00 (2006.01) ,A61P 35/00 (2006.01) ,A61P 39/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33
Medicinal preparations containing inorganic active ingredients
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
G
TRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
10
Treatment rooms for medical purposes
02
with artificial climate; with means to maintain a desired pressure, e.g. for germ-free rooms
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
H
PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
33
Bathing devices for special therapeutic or hygienic purposes
14
Devices for gas baths with ozone, hydrogen, or the like
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
7
Drugs for disorders of the blood or the extracellular fluid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
39
General protective or antinoxious agents
06
Free radical scavengers or antioxidants
Applicants:
MiZ株式会社 MIZ COMPANY LIMITED [JP/JP]; 神奈川県鎌倉市大船二丁目19番15号 2-19-15, Ofuna, Kamakura-shi, Kanagawa 2470056, JP
医療法人社団愈光会 INCORPORATED MEDICAL INSTITUTION YUKOKAI [JP/JP]; 東京都渋谷区元代々木町33番12号 33-12, Motoyoyogi-cho, Shibuya-ku, Tokyo 1510062, JP
Inventors:
青木 幸昌 AOKI Yukimasa; JP
平野 伸一 HIRANO Shinichi; JP
佐藤 文平 SATO Bunpei; JP
黒川 亮介 KUROKAWA Ryosuke; JP
Agent:
特許業務法人平木国際特許事務所 HIRAKI & ASSOCIATES; 東京都港区愛宕二丁目5-1 愛宕グリーンヒルズMORIタワー32階 Atago Green Hills MORI Tower 32F, 5-1, Atago 2-chome, Minato-ku, Tokyo 1056232, JP
Priority Data:
2016-25275327.12.2016JP
2017-23107230.11.2017JP
Title (EN) RADIATION DAMAGE PROTECTIVE AGENT
(FR) AGENT DE PROTECTION CONTRE LES DOMMAGES PAR RAYONNEMENT
(JA) 放射線障害防御剤
Abstract:
(EN) The present application provides: a radiation damage protective agent characterized by containing, as an active ingredient, hydrogen gas for treating or alleviating radiation damage suffered by a human patient who has experienced radiation exposure or who has undergone or is undergoing radiation therapy, the hydrogen gas being contained in a concentration of 18.5% by volume or less in a high-pressure capsule that exceeds standard atmospheric pressure; and a high-pressure capsule for administering a hydrogen gas treatment agent such as a radiation damage protective agent to patients, including humans.
(FR) La présente invention concerne un agent de protection contre les dommages par rayonnement, caractérisé en ce qu'il contient comme principe actif de l'hydrogène gazeux, visant à traiter ou soulager des dommages liés au rayonnement dont souffre un patient humain qui a subi une exposition à un rayonnement ou qui a subi, ou est en train de subir, une radiothérapie, l'hydrogène gazeux étant contenu sous une concentration de 18,5 % en volume ou moins au sein d'une capsule à haute pression qui dépasse la pression atmosphérique normale. L'invention concerne également une capsule à haute pression destinée à administrer un agent de traitement constitué d'hydrogène gazeux en tant qu'agent de protection contre les dommages liés au rayonnement à des patients, y compris des êtres humains.
(JA) この出願は、標準大気圧を超える高気圧カプセル内で、放射線被曝を受けた又は放射線療法を受けたもしくは受けるヒト患者の放射線障害を治療又は軽減するための、且つ18.5体積%以下の濃度で含む水素ガスを有効成分として含むことを特徴とする放射線障害防御剤、並びに、放射線障害防御剤等の水素ガス治療剤をヒトを含む患者に投与するための高気圧カプセルを提供する。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)