Search International and National Patent Collections
|1. (WO2018123945) DEPOT PREPARATION COMPRISING TAFLUPROST AND CITRIC ACID ESTER|
|Applicants:||SANTEN PHARMACEUTICAL CO., LTD.
|Title:||DEPOT PREPARATION COMPRISING TAFLUPROST AND CITRIC ACID ESTER|
Provided are: a depot preparation comprising tafluprost which can form depots easily and can maintain the depot-formed state for a long period so that tafluprost can be sustainably released over a long period of time after in vivo administration thereof; and a method for stabilizing tafluprost. The present invention pertains to a depot preparation comprising tafluprost and a trialkyl citrate and/or an acetyltrialkyl citrate, wherein the alkyl groups in the trialkyl citrate and the alkyl groups in the acetyltrialkyl citrate are either the same or different and each of these alkyl groups has 3-5 carbon atoms.