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1. (WO2018123906) COMPOSITION FOR EXTERNAL USE

Pub. No.:    WO/2018/123906    International Application No.:    PCT/JP2017/046238
Publication Date: Fri Jul 06 01:59:59 CEST 2018 International Filing Date: Sat Dec 23 00:59:59 CET 2017
IPC: A61K 31/192
A61K 9/08
A61K 47/10
A61K 47/18
A61K 47/22
A61P 29/00
Applicants: KOBAYASHI PHARMACEUTICAL CO., LTD.
小林製薬株式会社
Inventors: OKAMOTO, Hiroaki
岡本 浩明
Title: COMPOSITION FOR EXTERNAL USE
Abstract:
[Problem] To provide a composition for external use which contains a loxoprofen compound as an active ingredient, the composition being less apt to change to brown with the lapse of time. [Solution] A composition for external use which comprises either loxoprofen or a pharmaceutically acceptable salt thereof, a capsaicinoid, and a C1-4 alcohol, wherein the alcohol is contained in an amount of 55 mass% or larger with respect to the whole composition.