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1. (WO2018123856) TECHNOLOGY FOR SELECTIVE PROTEIN SECRETION IN FUNGUS

Pub. No.:    WO/2018/123856    International Application No.:    PCT/JP2017/046107
Publication Date: Fri Jul 06 01:59:59 CEST 2018 International Filing Date: Sat Dec 23 00:59:59 CET 2017
IPC: C12N 1/15
C12N 11/16
C12N 15/00
C12N 15/09
C12P 1/00
C12P 1/02
C12P 7/64
C12P 19/14
C12P 19/30
C12P 21/00
Applicants: KAGOSHIMA UNIVERSITY
国立大学法人鹿児島大学
KAKUI, CO., LTD.
カクイ株式会社
Inventors: TAMAKI Hisanori
玉置 尚▲徳▼
FUTAGAMI Taiki
二神 泰基
IWAMOTO Masataka
岩元 正孝
Title: TECHNOLOGY FOR SELECTIVE PROTEIN SECRETION IN FUNGUS
Abstract:
The purpose of the present invention is to provide: a method for easily obtaining a culture supernatant having a reduced amount of unwanted enzymes; a microorganism that can be used in said method; and a method for producing a target substance using said microorganism. The present invention relates to a modified fungus that expresses a fusion polynucleotide in which a polynucleotide coding for a GPI-added signal sequence is joined to a polynucleotide coding for an endogenously secreted enzyme, and also relates to a method for producing a target substance using said modified fungus.