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1. (WO2018122174) MICROFLUIDIC FLOW RESTRICTOR AND SYSTEM

Pub. No.:    WO/2018/122174    International Application No.:    PCT/EP2017/084418
Publication Date: Fri Jul 06 01:59:59 CEST 2018 International Filing Date: Sat Dec 23 00:59:59 CET 2017
IPC: A61M 5/14
A61M 5/168
Applicants: CEQUR SA
Inventors: GRAVESEN, Peter
MADSEN, Bo F.
Title: MICROFLUIDIC FLOW RESTRICTOR AND SYSTEM
Abstract:
Embodiments of the present invention relate to a microfluidic flow restrictor having a converging tapered inlet connected by a constant internal diameter section to a diverging tapered outlet having an outlet face and a smooth and gradual transition from the constant internal diameter section to the outlet face. This dual tapered capillary flow restrictor may be incorporated into a system such as a microfluidic circuit. Using a dual tapered capillary for accurate flow control together with a constant pressure source provides a more steady flow with reduced flow fluctuation caused by bubbles passing or pinning to the capillary end-face. Further, when connected in series, these dual tapered capillary flow restrictors may reduce noise in flow and pressure measurements, reduce bubble segmentation, and reduce bubble pinning.