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1. (WO2018121787) GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC CD137
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/121787 International Application No.: PCT/CN2017/120388
Publication Date: 05.07.2018 International Filing Date: 30.12.2017
IPC:
C12N 15/85 (2006.01) ,C12N 15/90 (2006.01) ,C12N 15/113 (2010.01) ,C07K 14/705 (2006.01) ,C12N 15/12 (2006.01) ,A01K 67/027 (2006.01) ,A61K 39/395 (2006.01) ,A61P 35/00 (2006.01)
Applicants: BEIJING BIOCYTOGEN CO., LTD[CN/CN]; Room 1201-1210 Building 3, No. 88 Kechuang 6 Street, BDA Beijing 101111, CN
Inventors: SHEN, Yuelei; CN
GUO, Yanan; CN
BAI, Yang; CN
ZHAO, Lei; CN
HUANG, Rui; CN
YAO, Jiawei; CN
ZHANG, Meiling; CN
Agent: BEIJING LINKTEC IP LAW AGENT(SPECIAL GENERAL PARTNERSHIP); Room 108 No.9 West Apartment, No.56 Zhichun Road, Haidian District Beijing 100086, CN
Priority Data:
201611256707.430.12.2016CN
201710873061.225.09.2017CN
201711473251.129.12.2017CN
Title (EN) GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC CD137
(FR) ANIMAL NON HUMAIN GÉNÉTIQUEMENT MODIFIÉ À CD137 HUMAIN OU CHIMÉRIQUE
Abstract: front page image
(EN) Genetically modified non-human animals that express a human or chimeric (e.g., humanized) CD137, and methods of use thereof are provided.
(FR) L'invention concerne des animaux non humains génétiquement modifiés qui expriment CD137 humain ou chimérique (par exemple, humanisé), et des méthodes d'utilisation de ceux-ci.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)