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1. (WO2018121669) PHARMACEUTICAL COMPOSITION FOR TREATING CANCER AND USE THEREOF
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Pub. No.: WO/2018/121669 International Application No.: PCT/CN2017/119360
Publication Date: 05.07.2018 International Filing Date: 28.12.2017
IPC:
A61K 31/7068 (2006.01) ,A61K 31/4412 (2006.01) ,A61K 31/53 (2006.01) ,A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7042
Compounds having saccharide radicals and heterocyclic rings
7052
having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706
containing six-membered rings with nitrogen as a ring hetero atom
7064
containing condensed or non-condensed pyrimidines
7068
having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
4412
having oxo groups directly attached to the heterocyclic ring
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
53
having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
陈晓华 CHEN, Xiaohua [CN/CN]; CN
Inventors:
陈晓华 CHEN, Xiaohua; CN
Agent:
北京中济纬天专利代理有限公司 BEIJING WITAL PATENT AGENCY CO., LTD.; 中国北京市 朝阳区东三环北路甲2号8号楼0549室陆薇薇 LU, Weiwei Room 0549, 5th Floor, 8th Building, Jia No. 2 East Sanhuan North Road, Chaoyang District Beijing 100027, CN
Priority Data:
201611257037.830.12.2016CN
Title (EN) PHARMACEUTICAL COMPOSITION FOR TREATING CANCER AND USE THEREOF
(FR) COMPOSITION PHARMACEUTIQUE DESTINÉE AU TRAITEMENT DU CANCER, ET UTILISATION CORRESPONDANTE
(ZH) 一种用于治疗癌症的药物组合物及其应用
Abstract:
(EN) A pharmaceutical composition and kit for treating cancer, being used to enhance anti-tumor effects of capecitabine and reduce side effects. The pharmaceutical composition comprises an anti-tumor effective amount of capecitabine, anti-tumor synergistically effective amount of gimeracil, and potassium oxonate in an effective amount for reducing side effects, and is used for treating 5-fluorouracil-sensitive mammalian tumors.
(FR) L'invention concerne une composition pharmaceutique et un kit permettant le traitement du cancer, qui sont utilisés pour augmenter les effets antitumoraux de la capécitabine et diminuer ses effets indésirables. La composition pharmaceutique comprend une quantité efficace d'un point de vue antitumoral de capécitabine, une quantité efficace d'un point de vue antitumoral synergique de giméracil, et de l'oxonate de potassium en une quantité efficace pour diminuer les effets indésirables, et est utilisée pour traiter des tumeurs de mammifère sensibles au 5-fluorouracile.
(ZH) 一种用于治疗癌症的药物组合物和试剂盒,用于增强卡培他滨的抗肿瘤效果且降低副作用,该药物组合物包含有抗肿瘤有效量的卡培他滨、抗肿瘤增效效应有效量的吉莫斯特以及降低副作用有效量的氧嗪酸钾,用于治疗对5-氟尿嘧啶敏感的哺乳动物的肿瘤。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)