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1. (WO2018121640) RECOMBINANT GROUP 2 ALLERGEN PROTEIN FROM DERMATOPHAGOIDES FARINAE, AND PREPARATION METHOD AND APPLICATION THEREOF

Pub. No.:    WO/2018/121640    International Application No.:    PCT/CN2017/119200
Publication Date: Fri Jul 06 01:59:59 CEST 2018 International Filing Date: Fri Dec 29 00:59:59 CET 2017
IPC: C12N 15/12
C07K 14/435
C12N 15/81
C12N 1/19
C07K 1/36
C07K 1/34
C07K 1/20
C07K 1/18
A61K 39/35
A61P 37/08
Applicants: ZONHON BIOPHARMA INSTITUTE, INC
江苏众红生物工程创药研究院有限公司
GENSUN INSTITUTE OF BIOMEDICINE CO., LTD
常州京森生物医药研究所有限公司
Inventors: MA, Bruce Yong
马永
FAN, Yu
范宇
WANG, Jun
王俊
WANG, Anliang
王安良
Title: RECOMBINANT GROUP 2 ALLERGEN PROTEIN FROM DERMATOPHAGOIDES FARINAE, AND PREPARATION METHOD AND APPLICATION THEREOF
Abstract:
Provided are an optimized Der f2 gene, a recombinant Der f2 protein encoded thereby, a vector comprising said gene, and a Pichia pastoris strain. Also provided are an expression method, a purification method, and an application of the recombinant Der f2 protein.