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1. WO2018121607 - BENZO[B]THIOPHENE AMIDE DERIVATIVE AND USE THEREOF

Publication Number WO/2018/121607
Publication Date 05.07.2018
International Application No. PCT/CN2017/118994
International Filing Date 27.12.2017
Chapter 2 Demand Filed 26.10.2018
IPC
C07D 409/12 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
409Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61K 31/33 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
CPC
A61K 31/33
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07D 409/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
409Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
Applicants
  • 山东大学 SHANDONG UNIVERSITY [CN]/[CN]
  • 济南成城生物技术有限公司 JINAN CHENGCHENG BIOTECHNOLOGY CO., LTD. [CN]/[CN]
Inventors
  • 宋淳 SONG, Chun
  • 张成城 ZHANG, Chengcheng
  • 黄牛 HUANG, Niu
  • 张承智 ZHANG, Chengzhi
  • 赵昕 ZHAO, Xin
  • 张衡 ZHANG, Heng
Agents
  • 中国国际贸易促进委员会专利商标事务所 CCPIT PATENT AND TRADEMARK LAW OFFICE
Priority Data
201611225728.X27.12.2016CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) BENZO[B]THIOPHENE AMIDE DERIVATIVE AND USE THEREOF
(FR) DÉRIVÉ DE BENZO[B]THIOPHÈNE AMIDE ET SON UTILISATION
(ZH) 苯并[b]噻吩酰胺类衍生物及其用途
Abstract
(EN)
Disclosed are a benzo[b]thiophene amide derivative and the use thereof. In particular, the present invention relates to a benzo[b]thiophene amide derivative having a structure of formula (I) or a pharmaceutically acceptable salt thereof, and the use of the compounds in regulating the activity of the Smoothened receptor or Hedgehog pathway.
(FR)
La présente invention concerne un dérivé de benzo[b]thiophène amide et son utilisation. En particulier, la présente invention concerne un dérivé de benzo[b]thiophène amide présentant une structure de formule (I) ou un sel pharmaceutiquement acceptable de ce dernier, et l’utilisation des composés dans la régulation de l’activité du récepteur Smoothened ou de la voie Hedgehog.
(ZH)
公开了苯并[b]噻吩酰胺类衍生物及其用途。具体地,涉及具有式(I)结构的苯并[b]噻吩酰胺类衍生物或其药学上可接受的盐,以及这些化合物在调节Smoothened受体或者Hedgehog通路活性中的用途。
Also published as
Latest bibliographic data on file with the International Bureau