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1. (WO2018121559) COMPOSITION OF MANNURONIC DICARBOXYLIC ACID
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Pub. No.: WO/2018/121559 International Application No.: PCT/CN2017/118843
Publication Date: 05.07.2018 International Filing Date: 27.12.2017
IPC:
A61K 31/7016 (2006.01) ,A61K 31/702 (2006.01) ,A61K 31/734 (2006.01) ,A61P 25/28 (2006.01) ,A61P 9/00 (2006.01) ,C08B 37/04 (2006.01) ,C07H 3/04 (2006.01) ,C07H 3/06 (2006.01) ,C07H 1/00 (2006.01)
[IPC code unknown for A61K 31/7016][IPC code unknown for A61K 31/702][IPC code unknown for A61K 31/734][IPC code unknown for A61P 25/28][IPC code unknown for A61P 9][IPC code unknown for C08B 37/04][IPC code unknown for C07H 3/04][IPC code unknown for C07H 3/06][IPC code unknown for C07H 1]
Applicants:
上海绿谷制药有限公司 SHANGHAI GREEN VALLEY PHARMACEUTICAL CO., LTD. [CN/CN]; 中国上海市 浦东张江高科技园区牛顿路421号 421 Niudun Road, Zhang Jiang Hi-Tech Park, Pudong New Area, Shanghai 201203, CN
中国科学院上海药物研究所 SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES [CN/CN]; 上海市浦东新区张江祖冲之路555号 555 Zuchongzhi RD., Zhangjiang, Hi-Tech Park, Pudong New Area Shanghai 201203, CN
Inventors:
耿美玉 GENG, Meiyu; CN
丁健 DING, Jian; CN
张真庆 ZHANG, Zhenqing; CN
肖中平 XIAO, Zhongping; CN
杜晓光 DU, Xiaoguang; CN
辛现良 XIN, Xianliang; CN
Agent:
北京市金杜律师事务所 KING & WOOD MALLESONS; 中国北京市 朝阳区东三环中路1号环球金融中心办公楼东楼20层 20th Floor, East Tower, World Financial Centre, No. 1 Dongsanhuan Zhonglu, Chaoyang District, Beijing 100020, CN
Priority Data:
PCT/CN2016/11387930.12.2016CN
Title (EN) COMPOSITION OF MANNURONIC DICARBOXYLIC ACID
(FR) COMPOSITION D'ACIDE DICARBOXYLIQUE MANNURONIQUE
(ZH) 甘露糖醛二酸的组合物
Abstract:
(EN) A mannuronic dicarboxylic acid oligosaccharide composition, which comprises mannuronic dicarboxylic acid of formula (III) or a pharmaceutically acceptable salt thereof, where n is an integer selected from 1-9, M is selected from 0, 1, or 2, m' is selected from 0 or 1, the total weight of mannuronic dicarboxylic acid for which n = 1-5 accounts for 80-95% of the total weight of the composition, and the ratio of the total weight of mannuronic dicarboxylic acid for which n = 1-3 to the total weight of mannuronic dicarboxylic acid for which N = 4-7 is between 1.0 and 3.5.
(FR) L'invention concerne une composition d'oligosaccharides d'acide dicarboxylique mannuronique, qui comprend de l'acide dicarboxylique mannuronique de formule (III) ou un sel pharmaceutiquement acceptable de celui-ci, n étant un nombre entier choisi de 1 à 9, M étant choisi parmi 0, 1 ou 2, m' étant choisi parmi 0 ou 1, le poids total de l'acide dicarboxylique mannuronique pour lequel n = 1 à 5 représentant 80 à 95 % du poids total de la composition, et le rapport du poids total de l'acide dicarboxylique mannuronique pour lequel n = 1 à 3 au poids total de l'acide dicarboxylique mannuronique pour lequel N = 4 à 7 étant compris entre 1,0 et 3,5.
(ZH) 一种甘露糖醛二酸寡糖组合,其包含具有式(III)的甘露糖醛二酸或其药学上可接受的盐,其中n为选自1-9的整数,m选自0,1或2,m'选自0或1,并且其中n=1-5的甘露糖醛二酸的重量总和占所述组合总重量的80-95%;n=1-3的甘露糖醛二酸的重量总和与n=4-7的甘露糖醛二酸重量总和的比例在1.0-3.5之间。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)