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|1. (WO2018121475) SINGLE-DOMAIN ANTIBODY RECOGNIZING COMPLEX FORMED BY HLA-A2 MOLECULE AND SLLMWITQC SHORT PEPTIDE|
|Applicants:||TIMMUNE BIOTECH INC.
|Title:||SINGLE-DOMAIN ANTIBODY RECOGNIZING COMPLEX FORMED BY HLA-A2 MOLECULE AND SLLMWITQC SHORT PEPTIDE|
Provided is a single-domain antibody capable of specifically recognizing an HLA-A2/SLLMWITQC complex. The single-domain antibody comprises CDR1, CDR2, and CDR3 amino acid sequences having a specific recognition effect. The single-domain antibody can be used in preparing various fusion proteins and polyspecific antibodies, and in preparing an antibody drug for treating melanoma, breast cancer, prostate cancer, lung cancer, ovarian cancer, thyroid cancer, liver cancer, bladder cancer, advanced gastric cancer, etc.