A footwear care machine, comprising a footwear care machine housing, a sealing door (3), a pressure-retaining box, a depressurized pump (13), a depressurized pump motor (15), a pressurized pump (14), a pressurized pump motor (16), a pressurized valve (11), a depressurized valve or an exhaust valve (12), a safety valve (10), and a washing liquid bottle or a washing gas bottle or a decomposition liquid bottle. The pressure-retaining box is provided inside the footwear care machine housing. The sealing door (3) forms a low pressure or vacuum sealing fitting with the pressure-retaining box. The depressurized pump (13) is provided on the pressure-retaining box. The depressurized pump (13) is connected to the external atmosphere by pipelines via the depressurized valve or the exhaust valve (12). When cleaning footwear, it is only necessary to first put the footwear into the pressure-retaining box, close the sealing door such that a low pressure or vacuum space is formed between the sealing door and the pressure-retaining box, and then press a start key on a keyboard.