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1. (WO2018108164) BORTEZOMIB PHARMACEUTICAL COMPOSITION AND APPLICATIONS THEREOF
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Pub. No.: WO/2018/108164 International Application No.: PCT/CN2017/116587
Publication Date: 21.06.2018 International Filing Date: 15.12.2017
IPC:
A61K 38/05 (2006.01) ,A61P 35/00 (2006.01) ,A61K 9/16 (2006.01) ,A61K 9/06 (2006.01) ,A61K 9/10 (2006.01) ,A61K 9/127 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
05
Dipeptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
16
Agglomerates; Granulates; Microbeadlets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
06
Ointments; Bases therefor
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
10
Dispersions; Emulsions
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
10
Dispersions; Emulsions
127
Liposomes
Applicants: NINGBO NINGRONG BIOPHARMA CO. LTD[CN/CN]; Building 1, No. 1200, North Xinghai Road, Ninghai County Ningbo, Zhejiang 315600, CN
Inventors: GAN, Yong; CN
ZHU, Quanlei; CN
ZHU, Chunliu; CN
JI, Liang; CN
JIN, Yuliang; CN
GUO, Shiyan; CN
Agent: KINGSOUND & PARTNERS; 11/F, Block B, KingSound International Center, 116 Zizhuyuan Road, Haidian District Beijing 100097, CN
Priority Data:
201611168699.816.12.2016CN
Title (EN) BORTEZOMIB PHARMACEUTICAL COMPOSITION AND APPLICATIONS THEREOF
(FR) COMPOSITION PHARMACEUTIQUE DE BORTÉZOMIB ET SES APPLICATIONS
(ZH) 一种硼替佐米药物组合物及其应用
Abstract:
(EN) A bortezomib pharmaceutical composition and applications thereof. The composition comprises the components in parts by weight: 0.1 to 200 parts of bortezomib, 0.1 to 500 parts of release rate regulation excipient, 0 to 1000 parts of micromolecule regulator and 0 to 2000 parts of injectable solvent. Applications of the bortezomib pharmaceutical composition in the preparation of drugs used for treating refractory/easily-reoccurring multiple myeloma.
(FR) L’invention concerne une composition pharmaceutique de bortézomib et ses applications. La composition comprend les composants en parties en poids : de 0,1 à 200 parties de bortézomib, de 0,1 à 500 parties d'excipient de régulation de taux de libération, de 0 à 1000 parties de régulateur de micromolécule et de 0 à 2000 parties de solvant injectable. L’invention concerne également des applications de la composition pharmaceutique de bortézomib dans la préparation de médicaments utilisés pour le traitement du myélome multiple réfractaire/facilement récurrent.
(ZH) 一种硼替佐米药物组合物及其应用,该组合物包含0.1-200重量份的硼替佐米、0.1-500重量份的释放速率调节用辅料,0-1000重量份的小分子调节剂,和0-2000重量份的药用可注射溶剂。硼替佐米药物组合物在制备用于治疗难治/复发多发性骨髓瘤的药物中的用途。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)