Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/108156 International Application No.: PCT/CN2017/116493
Publication Date: 21.06.2018 International Filing Date: 15.12.2017
C07D 471/04 (2006.01) ,C07D 403/12 (2006.01) ,C07D 409/14 (2006.01) ,A61K 31/38 (2006.01) ,A61K 31/395 (2006.01) ,A61P 9/00 (2006.01) ,A61P 9/12 (2006.01) ,A61P 35/00 (2006.01)
[IPC code unknown for C07D 471/04][IPC code unknown for C07D 403/12][IPC code unknown for C07D 409/14][IPC code unknown for A61K 31/38][IPC code unknown for A61K 31/395][IPC code unknown for A61P 9][IPC code unknown for A61P 9/12][IPC code unknown for A61P 35]
成都先导药物开发有限公司 HITGEN LTD. [CN/CN]; 中国四川省成都市 高新区冯家湾工业园科园南路88号3号研发楼1001号 1001, Building B3, Fengjiawan Industrial Park, No. 88, South Keyuan Road, High-Tech Zone Chengdu, Sichuan 610041, CN
李进 LI, Jin; CN
张登友 ZHANG, Dengyou; CN
冯静超 FENG, Jingchao; CN
谷浩 GU, Hao; CN
兰燕 LAN, Yan; CN
李偲 LI, Si; CN
陈伟 CHEN, Wei; CN
成都高远知识产权代理事务所(普通合伙) GAOYUNG INTELLECTUAL PROPERTY AGENCY(GENERAL PARTNERSHIP); 中国四川省成都市 高新区衣冠庙邮局A-42号信箱 The Yiguanmiao Post Office Box A-42, Hi-Tech Zone Chengdu, Sichuan 610041, CN
Priority Data:
(ZH) ROCK抑制剂及其应用
(EN) A ROCK inhibitor represented by formula (I) and a preparation method and application thereof. An experiment has demonstrated that the compound has good ROCK-inhibiting activity, and can be effectively used in treating a disease related to abnormal ROCK activity.
(FR) L'invention concerne un inhibiteur de ROCK représenté par la formule (I) et sa méthode de préparation et son application. Une expérience a démontré que le composé a une bonne activité inhibitrice de ROCK, et peut être efficacement utilisé dans le traitement d'une maladie liée à une activité anormale de ROCK.
(ZH) 式(I)所示的ROCK抑制剂及其制备方法和应用。试验表明,所述化合物具有良好的ROCK抑制活性,可以有效用于与ROCK活性异常疾病的治疗。
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)