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1. (WO2018108147) COMPOSITION, APPLICATION THEREOF AND TREATMENT METHOD

Pub. No.:    WO/2018/108147    International Application No.:    PCT/CN2017/116413
Publication Date: Fri Jun 22 01:59:59 CEST 2018 International Filing Date: Sat Dec 16 00:59:59 CET 2017
IPC: A61K 31/454
A61K 31/5377
A61K 31/4166
A61K 31/4439
A61K 31/573
A61K 31/57
A61K 31/5025
A61K 31/5685
A61K 31/365
A61P 35/00
Applicants: KANGPU BIOPHARMACEUTICALS, LTD.
康朴生物医药技术(上海)有限公司
Inventors: GE, Chuansheng
戈传生
LIAO, Baisong
廖柏松
LEE, Wen-Cherng
李文成
Title: COMPOSITION, APPLICATION THEREOF AND TREATMENT METHOD
Abstract:
Provided are a composition, an application thereof and a treatment method. The composition comprises a benzoheterocyclic compound represented by general formula (I), one or more from among a pharmaceutically acceptable salt thereof, a solvate, a crystal form, a cocrystal, a stereoisomer, an isotope compound, a metabolite and a prodrug, and an androgen receptor pathway modulator and/or a hormone drug. The composition and treatment method may effectively inhibit the growth of prostate cancer cells.