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1. (WO2018107236) NOVEL COMPOUNDS AS ANTI-MYCOBACTERIALS

Pub. No.:    WO/2018/107236    International Application No.:    PCT/AU2017/051394
Publication Date: Fri Jun 22 01:59:59 CEST 2018 International Filing Date: Sat Dec 16 00:59:59 CET 2017
IPC: C07K 5/037
A61K 38/04
A61K 38/07
A61P 11/00
A61P 31/04
A61P 31/06
A61P 31/08
Applicants: THE UNIVERSITY OF SYDNEY
Inventors: PAYNE, Richard J.
BRITTON, Warwick John
TRAN, Anh
TRAN, Wendy
Title: NOVEL COMPOUNDS AS ANTI-MYCOBACTERIALS
Abstract:
The present disclosure relates to antibacterial compounds. In particular, the compounds are for inhibiting the growth of bacteria, particularly Mycobacterium tuberculosis (Mtb), and/or targeting bacteria having phospho-MurNAc-pentapeptide translocase. The present disclosure also relates to compositions containing these compounds and methods of the use of these compounds and compositions.