Search International and National Patent Collections

1. (WO2018107205) RADIOLABELLED MATERIAL FOR TARGETED ADMINISTRATION

Pub. No.:    WO/2018/107205    International Application No.:    PCT/AU2017/000279
Publication Date: Fri Jun 22 01:59:59 CEST 2018 International Filing Date: Sat Dec 16 00:59:59 CET 2017
IPC: A61K 51/06
A61K 103/00
A61N 5/00
A61P 35/00
Applicants: THE AUSTRALIAN NATIONAL UNIVERSITY
Inventors: STEPHENS, Ross Wentworth
TREDWELL, Gregory David
KNOX, Karen Joanne
PHILIP, Lee Andrew
GREENLEES, Rebecca
BEATTIE, Keira
Title: RADIOLABELLED MATERIAL FOR TARGETED ADMINISTRATION
Abstract:
The invention relates to a radiolabelled material comprising a polymer, a radioactive isotope, and an immobilizing agent, wherein the immobilizing agent is capable of immobilizing the radioactive isotope on or in the polymer, and wherein the immobilizing agent is a macromolecule comprising a polycation with multiple pendant metal-chelating side-chains. The invention also relates to a process for making a radiolabelled material, to use of a radiolabelled material for the preparation of medicaments for treating cancer and/or for radiation imaging and to use of a radiolabelled material in the treatment of cancer. There is further described use of an immobilizing agent to immobilize a radioactive isotope on or in a polymer.