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1. (WO2018107201) HEPARANASE INHIBITORS AND USE THEREOF

Pub. No.:    WO/2018/107201    International Application No.:    PCT/AU2017/000271
Publication Date: Fri Jun 22 01:59:59 CEST 2018 International Filing Date: Thu Dec 14 00:59:59 CET 2017
IPC: C07D 403/14
C07D 413/12
C07D 413/06
C07D 413/14
C07D 403/04
C07D 405/06
C07D 403/06
C07D 239/95
C07D 403/12
A61K 31/498
A61P 35/00
A61P 27/02
A61P 3/00
Applicants: BETA THERAPEUTICS PTY LTD
Inventors: NELMS, Keats
SCHWARTZ, Brett
JACKSON, Colin
BANWELL, Martin
HAMMOND, Edward
Title: HEPARANASE INHIBITORS AND USE THEREOF
Abstract:
The invention relates to functionalized dihydro— and tetrahydro-quinazoline compounds, pharmaceutical compositions comprising such compounds, and the use of such compounds as heparanase inhibitors for the treatment of diseases or conditions related to heparanase.