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1. (WO2018107178) SYSTEMS AND METHODS FOR SEQUENCING T CELL RECEPTORS AND USES THEREOF
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Pub. No.: WO/2018/107178 International Application No.: PCT/US2017/065649
Publication Date: 14.06.2018 International Filing Date: 11.12.2017
IPC:
G06F 19/18 (2011.01) ,C12Q 1/6869 (2018.01) ,C12Q 1/6809 (2018.01)
G PHYSICS
06
COMPUTING; CALCULATING; COUNTING
F
ELECTRIC DIGITAL DATA PROCESSING
19
Digital computing or data processing equipment or methods, specially adapted for specific applications
10
Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
18
for functional genomics or proteomics, e.g. genotype-phenotype associations, linkage disequilibrium, population genetics, binding site identification, mutagenesis, genotyping or genome annotation, protein-protein interactions or protein-nucleic acid interactions
[IPC code unknown for C12Q 1/6869][IPC code unknown for C12Q 1/6809]
Applicants:
REGENERON PHARMACEUTICALS, INC. [US/US]; 777 OLD SAW MILL RIVER ROAD TARRYTOWN, New York 10591-6707, US
Inventors:
ZHANG, Wen; US
WANG, Bei; US
GUPTA, Namita; US
Agent:
BROWN, Charley F.; US
KATZ, Mitchell A.; US
MEADOWS, Brian C.; US
HATHCOCK, Kevin W.; US
MARTY, Scott D.; US
SHORTELL, D. Brian; US
ANDERSON, Joseph P.; US
CHOI, Wendy A.; US
JARVHOLM, E. Jonas; US
SCIASCIA-ZIRGER, Sandra; US
MILLER, Richard; US
KLIEM, Michele; US
ZIMMERMAN, Sommer; US
FLETCHER, Jason T.; US
LEVITIN, Galit; US
KHALAJ, Maha; US
TALCOTT, Jonathon A.; US
SZE, James Y.C.; US
SEGAL, Marc S.; US
CHIONCHIO, John A.; US
GOLDBERT, Elysa; US
GAUDET, Stephen; US
LANSBERY, Kristan; US
SMELAND, Tor; US
MIYAMOTO, Neil; US
COTTINGHAM, Frank; US
MALLON, Veronica; US
PATANKAR, Aparna; US
CHOI, Yong Jin; US
CHANG, Robert; US
JOHNSON, Mary; US
ZIPPIN, Margarita; US
WESTBERG, Christopher; US
GHOSH, Roshni; US
DI GABRIELE PETTI, Anna; US
GONT, Ilona; US
BOUSHEHRI, Darjush; US
COCCA, Brian; US
TRIOLO, Thomas; US
Priority Data:
62/432,52509.12.2016US
62/508,66719.05.2017US
Title (EN) SYSTEMS AND METHODS FOR SEQUENCING T CELL RECEPTORS AND USES THEREOF
(FR) SYSTÈMES ET PROCÉDÉS DE SÉQUENÇAGE DE RÉCEPTEURS DE CELLULES T ET LEURS UTILISATIONS
Abstract:
(EN) Disclosed herein are methods and systems that can reconstruct, extract, and/or analyze TCR sequences using short reads. The methods and systems can be applied to both single cell and bulk sequencing data.
(FR) L'invention concerne des procédés et des systèmes permettant de reconstruire, d'extraire et/ou d'analyser des séquences de TCR (récepteur des cellules T) à l'aide de lectures courtes. Ces procédés et ces systèmes peuvent être appliqués à la fois à des données de séquençage de cellule unique et de masse.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)