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1. (WO2018107168) DURABLE ENZYME-BASED BIOSENSOR AND PROCESS FOR DROP DEPOSITION IMMOBILIZATION
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Pub. No.: WO/2018/107168 International Application No.: PCT/US2017/065624
Publication Date: 14.06.2018 International Filing Date: 11.12.2017
IPC:
G01N 27/327 (2006.01) ,A61B 5/145 (2006.01) ,A61B 5/1468 (2006.01) ,A61B 5/1486 (2006.01) ,C09D 5/16 (2006.01) ,C09D 7/12 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27
Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
26
by investigating electrochemical variables; by using electrolysis or electrophoresis
28
Electrolytic cell components
30
Electrodes, e.g. test electrodes; Half-cells
327
Biochemical electrodes
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
1468
using chemical or electrochemical methods, e.g. by polarographic means
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
1486
using enzyme electrodes, e.g. with immobilised oxidase
C CHEMISTRY; METALLURGY
09
DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
D
COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
5
Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
16
Anti-fouling paints; Underwater paints
C CHEMISTRY; METALLURGY
09
DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
D
COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
7
Features of coating compositions, not provided for in group C09D5/88
12
Other additives
Applicants:
NORTHEASTERN UNIVERSITY [US/US]; 360 Huntington Avenue Boston, MA 02115, US
Inventors:
DU, Yunqing; US
WANG, Ming, L.; US
Agent:
HYMEL, Lin, J.; US
HJORTH, Beverly, E.; US
MAHANTA, Sanjeev, K.; US
Priority Data:
62/432,51309.12.2016US
Title (EN) DURABLE ENZYME-BASED BIOSENSOR AND PROCESS FOR DROP DEPOSITION IMMOBILIZATION
(FR) BIOCAPTEUR À BASE D’ENZYME DURABLE ET PROCÉDÉ D’IMMOBILISATION PAR DÉPÔT DE GOUTTE
Abstract:
(EN) A sensor having improved shelf life is provided for determining concentration of a biomarker in a liquid sample. The sensor functions by electrochemical detection and requires use of a biomolecule, e.g., an enzyme that catalyzes an electron transfer reaction specific for the biomarker. The sensor requires use of a quaternary ammonium compound as a bio-linker. It further requires crosslinking of the biomolecule for improved stability.
(FR) La présente invention concerne un capteur ayant une durée de conservation améliorée qui est utilisé pour déterminer la concentration d’un biomarqueur dans un échantillon liquide. Le capteur fonctionne par détection électrochimique et nécessite l’utilisation d’une biomolécule, par exemple, une enzyme qui catalyse une réaction de transfert d’électrons spécifique pour le biomarqueur. Le capteur nécessite l’utilisation d’un composé d’ammonium quaternaire en tant que biolieur. Il nécessite en outre la réticulation de la biomolécule pour une stabilité améliorée.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)