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1. (WO2018107020) AMINOGLYCOSIDE POTENTIATION FOR TREATMENT OF PULMONARY BACTERIAL INFECTION

Pub. No.:    WO/2018/107020    International Application No.:    PCT/US2017/065291
Publication Date: Fri Jun 15 01:59:59 CEST 2018 International Filing Date: Sat Dec 09 00:59:59 CET 2017
IPC: A61K 31/7036
A61K 31/198
A61K 33/06
Applicants: ENBIOTIX, INC.
Inventors: JOSEPH-MCCARTHY, Diane, M.
KOEVA, Martina, I.
Title: AMINOGLYCOSIDE POTENTIATION FOR TREATMENT OF PULMONARY BACTERIAL INFECTION
Abstract:
The present invention provides methods and formulations for treating or preventing bacterial infection in the lungs of a subject, including for controlling P. aeruginosa infection and/or colonization in the lungs of a patient having a chronic lung condition, such as cystic fibrosis (CF), non-cystic fibrosis bronchiectasis (non-CFBE), chronic obstructive pulmonary disorder (COPD), among others. In some embodiments, the invention provides methods and formulations for treating mycobacterial infection.