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1. (WO2018106997) DEVELOPMENT OF AMNION-LIKE TISSUE FROM HUMAN PLURIPOTENT STEM CELLS

Pub. No.:    WO/2018/106997    International Application No.:    PCT/US2017/065261
Publication Date: Fri Jun 15 01:59:59 CEST 2018 International Filing Date: Sat Dec 09 00:59:59 CET 2017
IPC: A61K 31/74
A61K 35/50
C12N 5/0789
Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
Inventors: FU, Jianping
GUMUCIO, Deborah
SHAO, Yue
TANIGUCHI, Kenichiro
ZHENG, Yi
ESFAHANI, Sajedeh Nasr
Title: DEVELOPMENT OF AMNION-LIKE TISSUE FROM HUMAN PLURIPOTENT STEM CELLS
Abstract:
The present disclosure provides compositions and methods employing stem cell-derived amnion tissue. In some embodiments, compositions (e.g., scaffolds and devices) and methods of generating amnion-like tissues from hPSCs are provided. In some embodiments, uses of such cells for research, compound screening and analysis, and therapeutics are provided.