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1. (WO2018106988) BIOLOGICALLY ACTIVE COMPOSITIONS CONTAINING TWO DIFFERENT CLASSES OF CHEMICAL COMPOUNDS FOR TREATING SOLID TUMORS

Pub. No.:    WO/2018/106988    International Application No.:    PCT/US2017/065241
Publication Date: Fri Jun 15 01:59:59 CEST 2018 International Filing Date: Sat Dec 09 00:59:59 CET 2017
IPC: A61K 31/551
A61P 35/00
Applicants: SMET PHARMACEUTICAL INC.
Inventors: FU, Tao
XIAO, Zuoxiang
Title: BIOLOGICALLY ACTIVE COMPOSITIONS CONTAINING TWO DIFFERENT CLASSES OF CHEMICAL COMPOUNDS FOR TREATING SOLID TUMORS
Abstract:
A pharmaceutical composition for treating a solid tumor includes using a combination of two different classes of chemicals: tricyclic thienotriazolodiazepin, a stain, and a pharmaceutical formulation. Using JQl as a representative of tricyclic thienotriazolodiazepin, and Lovastatin as a representative of statin, the combination has brought forth the achievement of successful treatment of solid tumors, especially with respect to liver tumor and lung tumor.