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1. (WO2018106988) BIOLOGICALLY ACTIVE COMPOSITIONS CONTAINING TWO DIFFERENT CLASSES OF CHEMICAL COMPOUNDS FOR TREATING SOLID TUMORS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/106988    International Application No.:    PCT/US2017/065241
Publication Date: 14.06.2018 International Filing Date: 08.12.2017
IPC:
A61K 31/551 (2006.01), A61P 35/00 (2006.01)
Applicants: SMET PHARMACEUTICAL INC. [US/US]; 5107 Pegasus Court, Suite L Frederick, MD 21704 (US)
Inventors: FU, Tao; (US).
XIAO, Zuoxiang; (US)
Agent: HO, David, K.; (US)
Priority Data:
62/432,224 09.12.2016 US
Title (EN) BIOLOGICALLY ACTIVE COMPOSITIONS CONTAINING TWO DIFFERENT CLASSES OF CHEMICAL COMPOUNDS FOR TREATING SOLID TUMORS
(FR) COMPOSITIONS BIOLOGIQUEMENT ACTIVES COMPORTANT DEUX CLASSES DIFFÉRENTES DE COMPOSÉS CHIMIQUES DESTINÉES AU TRAITEMENT DE TUMEURS SOLIDES
Abstract: front page image
(EN)A pharmaceutical composition for treating a solid tumor includes using a combination of two different classes of chemicals: tricyclic thienotriazolodiazepin, a stain, and a pharmaceutical formulation. Using JQl as a representative of tricyclic thienotriazolodiazepin, and Lovastatin as a representative of statin, the combination has brought forth the achievement of successful treatment of solid tumors, especially with respect to liver tumor and lung tumor.
(FR)L'invention concerne une composition pharmaceutique destinée au traitement d'une tumeur solide comprenant l'utilisation d'une association de deux classes différentes de produits chimiques : une thiénotriazolodiazépine tricyclique et une statine ; et une formulation pharmaceutique. Grâce au JQl en tant que représentant d'une thiénotriazolodiazépine tricyclique et à la lovastatine en tant que représentante d'une statine, l'association a permis d'obtenir le traitement efficace de tumeurs solides, en particulier en ce qui concerne la tumeur du foie et la tumeur du poumon.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)